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This paper is a great primer on how to study sex differences.īecker, J. Sex differences in the brain: the not so inconvenient truth. Perils and pitfalls of reporting sex differences. Multifaceted origins of sex differences in the brain. Sex and gender: modifiers of health, disease, and medicine. Synthesizing views to understand sex differences in response to early life adversity. This review synthesizes details of how antidepressants developed only in male rodents fail clinical testing when females are included in the trials.īath, K. Sex differences in the hypothalamic–pituitary–adrenal axis: an obstacle to antidepressant drug development? Br. Sex differences in vulnerability and resilience to stress across the life span. Life events and the 1-year prevalence of major depressive episode, generalized anxiety disorder, and panic disorder in a community sample. Work stress precipitates depression and anxiety in young, working women and men. Stress and psychiatric disorders: from categorical to dimensional approaches. Factor analysis shows that female rat behaviour is characterized primarily by activity, male rats are driven by sex and anxiety. Animal models of depression: what can they teach us about the human disease? Diagnostics 11, 123 (2021).įernandes, C., González, M. Sex bias and omission in neuroscience research is influenced by research model and journal, but not reported NIH funding. Evaluating sex as a biological variable in preclinical research: the devil in the details. Sex bias in neuroscience and biomedical research. The future of rodent models in depression research. Meeting report: can we make animal models of human mental illness? Biol. Are there differences between women’s and men’s antidepressant responses? Am. Are gender differences important for the clinical effects of antidepressants? Am. Gender differences in depression: findings from the STAR*D study. Gender differences in treatment response to sertraline versus imipramine in chronic depression. Sex differences in anxiety disorders: a review. Gender differences in chronic major and double depression. Sex differences in the psychopharmacological treatment of depression. US Department of Health & Human Services (2018). National Survey on Drug Use and Health (NSDUH). Twelve-month and lifetime prevalence and lifetime morbid risk of anxiety and mood disorders in the United States. Sex differences in anxiety and depression clinical perspectives. The team stumbles into the middle of an incredible rite of passage – and a war between Aliens and Predators.Altemus, M., Sarvaiya, N. Young Predators warriors are tested by fighting the Alien offspring. Moving from chamber to chamber, the horrific truth finally reveals itself: Predators have been keeping alive a captive Alien Queen who lays eggs at 100 year intervals. The chamber walls reconfigure unexpectedly, trapping members of the team and cutting them off from their colleagues. Inside the pyramid they find a matrix of chambers so technologically advanced that it becomes obvious that an extraterrestrial influence has been at work there for thousands of years. They discover a pyramid bearing a mixture of Aztec, Egyptian and Cambodian cultures. What they witness 2000 feet below the frozen surface at first excites, and then terrifies them. An incredible and horrific adventure begins when billionaire industrialist Charles Bishop Weyland gathers an international team of archaeologists, scientists and security experts, led by environmentalist and adventurer Alexa “Lex” Woods, to investigate a mysterious “heat bloom” emanating from deep under Antarctica. There, they make an even more terrifying discovery: two alien races at war. The discovery of an ancient pyramid buried under the Antarctic ice sends a team of scientists and adventurers to the frozen continent. The iconic monsters from two of the scariest film franchises ever battle each other on Earth in ALIEN VS.
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